Endocrine Abstracts

Introduction: Insulin resistance (IR) is the main pathogenic factor in polycystic ovary syndrome (PCOS) and its complications. Ceylon cinnamon (CC) is an herb with an insulin-sensitizing effect reported in diabetic patients.The aim of our study was to assess the efficiency of CC on the parameters of the IR in patients with (PCOS).Methods: We conducted a prospective interventional study, we included 13 patients with PCOS diagnosed according to the Rotterd...

Achieving glycemic targets is crucial in the management of diabetes mellitus. Insulin is the most effective hypoglycemic treatment for diabetes but its use can be associated with a risk of hypoglycemia.The aim of this study is to specify risk factors of hypoglycemia in insulin-treated patients.Patients and methods: This transversal study included 69 patients. They were females in 49.4% of cases (n=41). Mean age was 52 year...

Prolactinoma is a pituitary adenoma producing prolactin. Central hypogonadism is a major consequence of prolactinoma leading, in women, to menstrual troubles and infertility. The aim of this study was to specify gynecological characteristics of prolactinomas.Patients: This retrospective study included 28 female patients with prolactinoma. Mean age at diagnosis was 35.46 years (ext: 20–78). Mean serum prolactin level was 3442.4 ng/ml (ext: 31.9–...

Introduction: Type 1 diabetic women have generally more menstrual disorders than healthy women.Objectives: Identify the main mechanisms responsible of menstrual disorders in type1 diabetic women.Patients and methods: We conducted a comparative transversal study including 70 patients with type 1 diabetes: Thirty-three having menstrual disorders (group M) and 37 with regular menses (control group T).We compared...

Background: Although the most common causes of hypokalemia are diuretic use and gastrointestinal losses, elevated cortisol levels can also cause hypokalemia through its effects on the renin-angiotensin-aldosterone system.Case report: A 56-year-old woman with a history of diabetes mellitus and hypertension, presented to our emergency department with fast progressing generalized weakness, abdominal discomfort and diarrhea. Digestive tract diseases were rul...

IntroductionCerebral tuberculomas are a rare form of tuberculosis due to the hematogenous spread of Mycobacterium Tuberculosis (MT). Pituitary localization is exceptionally uncommon with total reported cases in the literature fewer than a hundred. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the rare case of a patient diagnosed with a primary pituitary stalk tuberculosis.Observation...

IntroductionThyrotropin-secreting pituitary adenoma is a rare cause of hyperthyroidism which must be differentiated from other etiologies of inappropriate TSH secretion.Observation:We report the case of a 49 years old male patient with no particular pathological history, addressed for thyrotoxicosis (weight loss, irritability, thermophobia, dyspnea and palpitation) with no goiter or ophtalmopathy. Echocardiog...

Introduction Growth hormone (GH ) deficiency is a rare but not exceptional cause of statural delay in children. The results of GH stimulation tests and the exploration of other pituitary axes allow us to conclude on the nature of the deficiency: total or partial and its possible association with other pituitary deficits.MethodsThis is a retrospective descriptive study including 75 patients followed for congen...

IntroductionHematological abnormalities are frequently observed in hyperthyroidism and are part of complex, multifactorial pathogenetic mechanisms that are still poorly understood, which can affect the three hematopoietic lineages in isolation or in combination. For the endocrinologist, they raise the issue of the risk of their aggravation under the hamatotoxic effect of antithyroid drugs (ATDs).Case presentation<p class="abste...

IntroductionGrowth hormone deficiency (GHD) is a rare cause of statural retardation in children. The diagnosis is evoked in front of a bundle of anamnestic, clinical and radiological arguments. Treatment consists of substitution by recombinant GH with the aim of restoring normal size. There is interindividual variability in the response to treatment. We therefore proposed to study the response to treatment as well as the predictive factors of this respon...